Evaluating Alternative Delivery Models for Arthritis Self-Management Interventions
(PI: Christine Pellegrini, PhD.; Co-I: Sara Wilcox, PhD.)
This study aims to evaluate a phone-based version of the Walk with Ease program in
adults with arthritis in a randomized controlled trial. Outcomes to be examined include
pain, function, physical activity, depressive symptoms, self-efficacy, work loss,
and healthcare utilization.
Funded by The Centers for Disease Control and Prevention - U48DP006401 (9/30/2021-9/29/2024)
Physical Activity and Weight Loss to Improve Function and Pain After Total Knee Replacement
(PI: Christine Pellegrini, Ph.D.; Co-I's: Brian Burnikel, MD., Brian Chen, JD, Ph.D.,
Elizabeth Regan, Ph.D., Gabrielle Turner-McGrievy, Ph.D., Philip Wessinger, Sara Wilcox,
The purpose of the current project is to evaluate the effectiveness of the PACE weight
loss program in adults after TKR in a fully-powered two-arm randomized controlled
Funded by the National Institute of Aging (NIA) - R01AG070004 (7/15/2021 - 6/30/2026)
Reducing Sedentary Time using an Innovative mHealth Intervention among Total Knee
Replacement Patients (PI: Christine Pellegrini, Ph.D.; Co-I's: Sara Wilcox, Ph.D.,
Julia Lee, Ph.D.)
The purpose of this study is to examine the innovative approach of decreasing sedentary time prior to targeting physical activity
in adults after TKR and determine if a remotely-delivered, mHealth sedentary reduction
intervention can decrease sedentary time.
Funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (4/1/2020 - 1/23/2023)
Energize! Internet-Delivered Physical Activity Program for Adults with Knee Replacement
(PI: Christine Pellegrini, Ph.D.; Co-I: Chih-Hsiang Yang, Ph.D.)
The purpose of this study is to examine the effects of an internet-based physical
activity program on moderate to vigorous intensity physical activity (MVPA), pain,
self-reported physical function, and cognitive function in adults with TKR at 3 months
(post intervention) and 6 months (maintenance).
Funded by The University of South Carolina Office of Reserch and Health Sciences (7/1/2023
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